Findings from Beaumont Hospital in Amyotrophic Lateral Sclerosis Provides New Insights (Measurement of Social Cognition in Amyotrophic Lateral Sclerosis: A Population Based Study)
By a News Reporter-Staff News Editor at Pain & Central Nervous System Week Research findings on Neurodegenerative Diseases and Conditions - Amyotrophic Lateral Sclerosis are discussed in a new report. According to news reporting from Dublin, Ireland, by NewsRx journalists, research stated, "Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease. Executive dysfunction is common in patients with ALS, with up to 50% of patients performing within an impaired range."
The news correspondents obtained a quote from the research from Beaumont Hospital, "There is evidence that social cognitive deficits associated with ALS are a function of deficits in executive function. The 'Reading the Mind in the Eyes' Test is a recognized test of social cognitive function, although the reliability of this instrument remains to be established. Patients with ALS (n=106), and age and IQ matched controls (n=50) were recruited and asked to perform the Reading the Mind in the Eyes Test as part of an on-going population-based study of cognitive function. ALS patients were sub-stratified based on the presence, and/or extent of executive dysfunction. Cronbach's Alpha of .73 was observed, indicating good reliability on this measure. Split-half reliability analysis further confirms these findings (p=0.826). The Reading the Mind in the Eyes test had excellent psychometric properties when discriminating between ALS patients who are cognitively intact, and those who have executive impairment, with an overall medium difficulty. There was a large magnitude significant difference between patients and controls (p <0.001; e2=.19). Post-hoc analysis revealed that controls performed significantly higher than patients with executive impairment (p <0.001), and patients with single executive deficits (p=0.002). Executive dysfunction impacts on social cognitive performance. This study contributes not only to the psychometric knowledge of this measure, but also to the usability, efficacy, and reliability of social cognitive assessment in ALS."
According to the news reporters, the research concluded: "Using population-specific normative data, we confirm the Reading the Mind in the Eyes Test is a reliable measure of social cognitive processes in ALS."
For more information on this research see: Measurement of Social Cognition in Amyotrophic Lateral Sclerosis: A Population Based Study. Plos One, 2016;11(8):e0160850. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)
Our news journalists report that additional information may be obtained by contacting T. Burke, Dept. of Psychology, Beaumont Hospital, Dublin, 9, Ireland. Additional authors for this research include M. Pinto-Grau, K. Lonergan, M. Elamin, P. Bede, E. Costello, O. Hardiman and N. Pender (see also Neurodegenerative Diseases and Conditions - Amyotrophic Lateral Sclerosis).
Keywords for this news article include: Dublin, Europe, Ireland, Neurology, Epidemiology, Motor Neuron Disease, TDP 43 Proteinopathies, Amyotrophic Lateral Sclerosis, Spinal Cord Diseases and Conditions, Neuromuscular Diseases and Conditions, Neurodegenerative Diseases and Conditions, Central Nervous System Diseases and Conditions.
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