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 The leading web portal for pharmacy resources, news, education and careers January 21, 2019
Pharmacy Choice - Pharmaceutical News - Studies by X.H. Guo and Co-Authors Describe New Findings in Drug Delivery Systems (Preparation and Evaluation of Multifunctional Autofluorescent Magnetic Nanoparticle-Based Drug Delivery Systems Against Mammary Cancer) - January 21, 2019

Pharmacy News Article

 1/10/19 - Studies by X.H. Guo and Co-Authors Describe New Findings in Drug Delivery Systems (Preparation and Evaluation of Multifunctional Autofluorescent Magnetic Nanoparticle-Based Drug Delivery Systems Against Mammary Cancer)

By a News Reporter-Staff News Editor at Pharma Business Week Investigators publish new report on Drugs and Therapies - Drug Delivery Systems. According to news reporting from Zhengzhou, People's Republic of China, by NewsRx journalists, research stated, "The Fe3O4@C@NaYF4:Yb, Er nanocarriers of multifunction were synthesized. The mitoxantrone was selected as model drug, and these nanoparticles have high drug loading (0.63 mg/mg)."

The news correspondents obtained a quote from the research, "The temperature of Fe3O4@C@NaYF4:Yb, Er in water reached 60 degrees C with 808 nm irritation (2.5 W/cm(2)). The cumulative release of these nano drug carriers significantly increased because of the increase in temperature, and the 4T1 cell growth inhibition rates were 59.15%, almost 2.25-fold higher than mitoxantrone group (p < 0.05). Because the nanoparticles had autofluorescence under 808 nm irritation, the nanocarriers could be traced in both in vitro and in vivo studies. Based on magnetic field, the fluorescence signal of these nano drug carriers could be observed at tumor region during 2-9 h in vivo study. The nanocarriers with magnetic and 808 nm laser group, tumor growth inhibition rate achieved almost 83.14%."

According to the news reporters, the research concluded: "These nanoparticles are an outstanding potential carrier for antitumor drugs, which can improve curative effect for tumor while reducing toxicity."

For more information on this research see: Preparation and Evaluation of Multifunctional Autofluorescent Magnetic Nanoparticle-Based Drug Delivery Systems Against Mammary Cancer. Journal of Pharmaceutical Sciences, 2018;107(10):2694-2701. Journal of Pharmaceutical Sciences can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Wiley-Blackwell - www.wiley.com/; Journal of Pharmaceutical Sciences - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1520-6017)

Our news journalists report that additional information may be obtained by contacting X.H. Guo, Henan Key Lab Targeted Therapy & Diag Tumor & Maj, Zhengzhou 450001, Henan, People's Republic of China. Additional authors for this research include J.Y. Zhang, X. Li, Z. Li and Z.Z. Zhang (see also Drugs and Therapies - Drug Delivery Systems).

(Our reports deliver fact-based news of research and discoveries from around the world.)



Copyright 2019, NewsRx LLC

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