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 The leading web portal for pharmacy resources, news, education and careers March 20, 2019
Pharmacy Choice - Pharmaceutical News - Researchers Submit Patent Application, "Device For Controlled Dispensation Of Liquid Medicament And Method Of Vaporization Control", for Approval (USPTO 20180369516) - March 20, 2019

Pharmacy News Article

 1/10/19 - Researchers Submit Patent Application, "Device For Controlled Dispensation Of Liquid Medicament And Method Of Vaporization Control", for Approval (USPTO 20180369516)

By a News Reporter-Staff News Editor at Pharma Business Week From Washington, D.C., NewsRx journalists report that a patent application by the inventor ADELSON, Robert (Vaughn, CA), filed on June 26, 2018, was made available online on December 27, 2018 (see also Resolve Digital Health Inc.).

The patent's assignee is Resolve Digital Health Inc. (Toronto, Canada).

News editors obtained the following quote from the background information supplied by the inventors: "Background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed invention, or that any publication specifically or implicitly referenced is prior art

"Therapeutic vaporizers provide an alternative drug-delivery method that permits patient to inhale vaporized medication rather than swallow a pill, or drink or inject medication. A variety of vaporizers and inhalation devices for vaporizing herbal oils and medicated liquids for pulmonary delivery have been developed and some of them are commercially available. These devices generally utilize drop dispensing systems that dispense liquid medication in droplet form to a heating assembly for vaporization. However, the drop volume or size produced by the existing dispensing mechanism is often inconsistent and non-replicable leading to inaccurate dosing of medications. As the dosage provided by a therapeutic vaporizer dependent upon the size of drops produced, drop dispensers that produce drops having sizes different than the desired or expected drop size may in turn yield medicament dosages that differ from the calculated and expected dosage. Further, the existing vaporizers or liquid dispensing systems do not provide for a method to control the volume of liquid that is dispensed for vaporization nor the volume of vapor produced and, as a result, cannot provide consistent and measurable doses of vaporized medication for pulmonary administration.

"Further, the existing vaporizers or liquid dispensing systems fail entirely to provide provisions for monitoring and recording critical information including size and number of drops dispensed for vaporization, and for analyzing the gathered data in a way that would be useful for either therapy or in a clinical setting. Another disadvantage of the prior art devices is that they provide no provision for communication with external networks or other functional units for recording critical data relating to usage of the medicament dispensing system and dosage of medicinal product for subsequent clinical analysis.

"Accordingly, it would be advantageous to provide a device that dispenses precise, replicable and consistent metered drops of liquid medication, and ensures that the dispensed drops can be vaporized in a manner that provides patients with a predictable dose. Another advantage would be to provide a liquid dispensing device with features to monitor and record size and number of drops dispensed for vaporization and number of doses remaining in the device thereby enhancing patient clinical care. Yet another advantage would be to provide a liquid dispensing device that is communicable in a web enabled environment to implement an effective medication management system.

"The present invention satisfies the existing needs, as well as others, and overcomes the deficiencies found in the prior art.

"All publications herein are incorporated by reference to the same extent as if each individual publication or patent application were specifically and individually indicated to be incorporated by reference. Where a definition or use of a term in an incorporated reference is inconsistent or contrary to the definition of that term provided herein, the definition of that term provided herein applies and the definition of that term in the reference does not apply.

"In some embodiments, the numbers expressing quantities of ingredients, properties such as concentration, reaction conditions, and so forth, used to describe and claim certain embodiments of the invention are to be understood as being modified in some instances by the term 'about.' Accordingly, in some embodiments, the numerical parameters set forth in the written description and attached claims are approximations that can vary depending upon the desired properties sought to be obtained by a particular embodiment. In some embodiments, the numerical parameters should be construed in light of the number of reported significant digits and by applying ordinary rounding techniques. Notwithstanding that the numerical ranges and parameters setting forth the broad scope of some embodiments of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as practicable. The numerical values presented in some embodiments of the invention may contain certain errors necessarily resulting from the standard deviation found in their respective testing measurements.

"As used in the description herein and throughout the claims that follow, the meaning of 'a,' 'an,' and 'the' includes plural reference unless the context clearly dictates otherwise. Also, as used in the description herein, the meaning of 'in' includes 'in' and 'on' unless the context clearly dictates otherwise.

"The recitation of ranges of values herein is merely intended to serve as a shorthand method of referring individually to each separate value falling within the range. Unless otherwise indicated herein, each individual value is incorporated into the specification as if it were individually recited herein. All methods described herein can be performed in any suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g. 'such as') provided with respect to certain embodiments herein is intended merely to better illuminate the invention and does not pose a limitation on the scope of the invention otherwise claimed. No language in the specification should be construed as indicating any non-claimed element essential to the practice of the invention.

"Groupings of alternative elements or embodiments of the invention disclosed herein are not to be construed as limitations. Each group member can be referred to and claimed individually or in any combination with other members of the group or other elements found herein. One or more members of a group can be included in, or deleted from, a group for reasons of convenience and/or patentability. When any such inclusion or deletion occurs, the specification is herein deemed to contain the group as modified thus fulfilling the written description of all groups used in the appended claims."

As a supplement to the background information on this patent application, NewsRx correspondents also obtained the inventor's summary information for this patent application: "In an aspect, the present disclosure relates to a drop dispenser device comprising: a liquid reservoir for holding a liquid medicament to be vaporized; a dispensing opening through which the liquid medicament is adapted to pass during a dispensing operation of the dispenser; and a dispensing mechanism configured to generate predetermined droplets of the liquid medicament, and expel the generated droplets through the dispensing opening in a selected liquid amount and at a selected frequency, upon activation of the dispensing mechanism.

"In another aspect, the drop dispenser dispenses accurate metered droplets of the liquid medicament on a consistent and replicable basis to a heating assembly for subsequent evaporation. In another aspect, the liquid medicament can be a herbal oil such as cannabis oil/extract.

"In another aspect, the device can enable monitoring and recording of size and number of droplets dispensed for vaporization and number of doses remaining in the dispenser.

"In yet another aspect, the device can enable maintenance of records of droplet consumption on a central storage device such as on a cloud/server, wherein the records are accessible, from the central storage device, to one or more stakeholders based on permissions granted by user of said device.

"In another aspect, the records can be automatically processed to enable determination of impact of droplet consumption on said user, based on which, treatment plan of said user is dynamically revised.

"In yet another aspect, the proposed device can further include a communication module configured to communicate droplet consumption data in real-time or on as required basis to one or more secondary users.

"In another aspect, the liquid medicament can be a combination of one or more liquids that are combined in a defined ratio prior to vaporization.

"In yet another aspect, size of the generated droplets can be controlled by any or a combination of execution of a set of instructions that are stored in memory unit of the device, or through an application configured in a portable computing device that the drop dispenser device is operatively coupled with.

"The present disclosure relates to a method comprising: holding, in a liquid reservoir of a drop dispenser device, a liquid medicament to be vaporized; adapting the liquid medicament to pass through a dispensing opening during a dispensing operation of the drop dispenser device; and generating, based on configuration of a dispensing mechanism that is configured in the drop dispenser device, predetermined droplets of the liquid medicament so as to expel the generated droplets through the dispensing opening in a selected liquid amount and at a selected frequency, upon activation of the dispensing mechanism.

"In another aspect, the size of the generated droplets can be controlled by any or a combination of execution of a set of instructions/signals that can be stored in memory unit of the device, or through an application/app configured in a portable computing device (such as a mobile/smart phone, wearable device, laptop, etc), that the drop dispenser device is operatively coupled with, for instance, through Wi-Fi, wireless connection, or Bluetooth, etc.

"In another aspect, configuration of the dispensing mechanism can be controlled through a portable computing device that can operatively be coupled with the drop dispenser device through a wireless connection in a manner such that signals for configuration of any or a combination of droplet size, liquid concentration in each droplet, number of droplets to be dispensed, frequency of dispensation, duration of dispensation in each iteration, are transmitted from the portable computing device and processed through a micro-controller configured in the drop dispenser device. The portable computing device can be coupled with a plurality of drop dispenser devices, each drop dispenser device of said plurality drop dispenser devices being associated with a unique identifier that is used in the operational instructions transmitted by said portable computing device to enable identification of the drop dispenser device for which the operational instructions are meant. In an aspect, the operational instructions can be encrypted by said portable computing device, and decrypted using a decryption key by the drop dispenser device.

"According to one aspect of the present disclosure, there is provided a drop dispenser capable of dispensing precise, replicable and consistent metered drops of liquid medicament for subsequent vaporization, and ensures that the dispensed drops can be vaporized in a manner that provides patients with a predictable dose. In an aspect, the drop dispenser can include: a liquid reservoir for holding a liquid medicament to be vaporized; a dispensing opening through which the liquid medicament is adapted to pass during a dispensing operation of the dispenser; and a dispensing mechanism configured to generate predetermined droplets of medicament and expel the droplets through the dispensing opening in a selected liquid amount and a selected frequency, upon activation of the dispensing mechanism.

"In an embodiment, the drop dispenser disclosed herein can dispense accurately metered drops of herbal oil on a consistent and replicable basis to a heating assembly for subsequent evaporation.

"In an aspect, the drop dispenser disclosed herein can incorporate smart features to monitor and record size and number of drops dispensed for vaporization and number of doses remaining in the dispenser thereby enhancing patient clinical care. The maintained records can help in allowing doctors and patients to gain a better understanding of how the medication is functioning to develop a customized treatment program.

"In an aspect, the disclosed drop dispenser can further incorporate means to communicate data in real time or on as required basis to various stakeholders such as doctor, care giver, drug stores, pharmaceutical companies etc. The means for communication can be a wireless communication means that can enable data transfer from the drop dispenser to external functional units or networks. Communication between the drop dispenser and external functional units or networks may be accomplished through any suitable communication channels such as Bluetooth, Wi-Fi, GSM communication means such as 3G etc.

"Various objects, features, aspects and advantages of the inventive subject matter will become more apparent from the following detailed description of preferred embodiments, along with the accompanying drawing figures in which like numerals represent like components."

The claims supplied by the inventors are:

"1. A drop dispenser device comprising: a liquid reservoir for holding a liquid medicament to be vaporized; a dispensing opening through which the liquid medicament is adapted to pass during a dispensing operation of the dispenser; and a dispensing mechanism configured to generate predetermined droplets of the liquid medicament, and expel the generated droplets through the dispensing opening in a selected liquid amount and at a selected frequency, upon activation of the dispensing mechanism.

"2. The drop dispenser device of claim 1, wherein the drop dispenser dispenses accurate metered droplets of the liquid medicament on a consistent and replicable basis to a heating assembly for subsequent evaporation.

"3. The drop dispenser device of claim 1, wherein the liquid medicament is herbal oil.

"4. The drop dispenser device of claim 1, wherein said device enables monitoring and recording of size and number of droplets dispensed for vaporization and number of doses remaining in the dispenser.

"5. The drop dispenser device of claim 1, wherein said device enables maintenance of records of droplet consumption on a central storage device, said records being accessible from said central storage device to one or more stakeholders based on permissions granted by user of said device.

"6. The drop dispenser device of claim 5, wherein said records are automatically processed to enable determination of impact of droplet consumption on said user, based on which, treatment plan of said user is dynamically revised.

"7. The drop dispenser device of claim 1, wherein the device further includes a communication module configured to communicate droplet consumption data in real-time or on as required basis to one or more secondary users.

"8. The drop dispenser device of claim 1, wherein the liquid medicament is a combination of one or more liquids that are combined in a defined ratio prior to vaporization.

"9. The drop dispenser device of claim 1, wherein size of the generated droplets is controlled by any or a combination of execution of a set of instructions that are stored in memory unit of the device, or through an application configured in a portable computing device that the drop dispenser device is operatively coupled with.

"10. A method comprising: holding, in a liquid reservoir of a drop dispenser device, a liquid medicament to be vaporized; adapting the liquid medicament to pass through a dispensing opening during a dispensing operation of the drop dispenser device; and generating, based on configuration of a dispensing mechanism that is configured in the drop dispenser device, predetermined droplets of the liquid medicament so as to expel the generated droplets through the dispensing opening in a selected liquid amount and at a selected frequency, upon activation of the dispensing mechanism.

"11. The method of claim 10, wherein the liquid medicament is an extract of cannabis.

"12. The method of claim 10, wherein said device enables monitoring and recording of size and number of droplets dispensed for vaporization and number of doses remaining in the dispenser.

"13. The method of claim 10, wherein said device enables maintenance of records of droplet consumption on a central storage device, said records being accessible from said central storage device to one or more stakeholders based on permissions granted by user of said device.

"14. The method of claim 10, wherein said records are automatically processed to enable determination of impact of droplet consumption on said user, based on which, treatment plan of said user is dynamically revised.

"15. The method of claim 10, wherein the device further includes a communication module configured to communicate droplet consumption data in real-time or on as required basis to one or more secondary users.

"16. The method of claim 10, wherein the liquid medicament is a combination of one or more liquids that are combined in a defined ratio prior to vaporization.

"17. The method of claim 10, wherein size of the generated droplets is controlled by any or a combination of execution of a set of instructions that are stored in memory unit of the device, or through an application configured in a portable computing device that the drop dispenser device is operatively coupled with.

"18. The method of claim 10, wherein the configuration of the dispensing mechanism is controlled through a portable computing device that is operatively coupled with the drop dispenser device through a wireless connection in a manner such that signals for configuration of any or a combination of droplet size, liquid concentration in each droplet, number of droplets to be dispensed, frequency of dispensation, duration of dispensation in each iteration, are transmitted from the portable computing device and processed through a micro-controller configured in the drop dispenser device.

"19. The method of claim 18, wherein the portable computing device is coupled with a plurality of drop dispenser devices, each drop dispenser device of said plurality drop dispenser devices being associated with a unique identifier that is used in the operational instructions transmitted by said portable computing device to enable identification of the drop dispenser device for which the operational instructions are meant.

"20. The method of claim 19, wherein the operational instructions are encrypted by said portable computing device, and decrypted using a decryption key by the drop dispenser device."

For additional information on this patent application, see: ADELSON, Robert. Device For Controlled Dispensation Of Liquid Medicament And Method Of Vaporization Control. Filed June 26, 2018 and posted December 27, 2018. Patent URL: http://appft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220180369516%22.PGNR.&OS=DN/20180369516&RS=DN/20180369516

(Our reports deliver fact-based news of research and discoveries from around the world.)



Copyright 2019, NewsRx LLC

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