Investigators at Technion-Israel Institute of Technology Discuss Findings in Drug Delivery Systems (Dielectrophoretic characterization and isolation of jellyfish stinging capsules)
By a News Reporter-Staff News Editor at Electronics Newsweekly New research on Drugs and Therapies - Drug Delivery Systems is the subject of a report. According to news reporting from Haifa, Israel, by VerticalNews journalists, research stated, "Jellyfish stinging capsules known as nematocysts are explosive, natural-injection systems with high potential as a natural drug-delivery system. These organelles consist of a capsule containing a highly folded thin needle-like tubule and a matrix highly concentrated with charged constituents that enable the tubule to fire and penetrate a target."
The news correspondents obtained a quote from the research from the Technion-Israel Institute of Technology, "For the purpose of using these nematocysts as drug delivery system it is first required to purify subpopulations from heterogeneous population of capsules and to investigate each subpopulation's distinct function and characteristics. Here, the nematocysts' dielectric properties were experimentally investigated using dielectrophoretic and electrorotational spectra with best fits derived from theoretical models. The dielectric characterization adds to our understanding of the nematocysts' structure and function and is necessary for the dielectrophoretic isolation and manipulation of populations. As expected, the effect of monovalent and divalent exchange cations resulted in higher inner conductivity for the NaCl treated capsules; this result stands in agreement with their relative higher osmotic pressure."
According to the news reporters, the research concluded: "In addition, an efficient dielectrophoretic isolation of different nematocyst subpopulations was demonstrated, paving the way to an understanding of nematocysts' functional diversity and the development of an efficient drug delivery platform."
For more information on this research see: Dielectrophoretic characterization and isolation of jellyfish stinging capsules. Electrophoresis, 2017;38(16):1996-2003. Electrophoresis can be contacted at: Wiley, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Electrophoresis - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1522-2683)
Our news journalists report that additional information may be obtained by contacting G. Yossifon, Technion Israel Inst Technol, Fac Mech Engn, Micro & Nanofluid Lab, IL-32000 Haifa, Israel. Additional authors for this research include D. Capelin, G. Piriatinskiy, T. Lotan and S. Park.
Keywords for this news article include: Haifa, Israel, Asia, Drug Delivery Systems, Drugs and Therapies, Technion-Israel Institute of Technology.
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